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Utility of Nebulized Hypertonic Saline in the Treatment of Viral Bronchiolitis

Posted September 6th, 2008 by topolho
in
Author Name(s):
Howard Topol, MD
Reviewer Name:
Chris Feudtner, MD, PhD, MPH
Clinical Question:

Should 3% nebulized hypertonic saline be used to treat infants hospitalized with viral bronchiolitis?

Atrovent and Asthma Beyond the Emergency Department

Posted March 20th, 2008 by lasaj
in
Author Name(s):
Javier J. Lasa, MD and Amy Cohen, MD
Reviewer Name:
Angela Ellison, MD
Clinical Question:

Does nebulized ipratropium bromide (Atrovent) have a clinically significant effect in treating moderate to severe asthma exacerbations in hospitalized pediatric patients?

Does early initiation of parenteral nutrition improve the outcomes of critically ill neonates?

Posted March 17th, 2008 by giacconea
in
Author Name(s):
Annie Giaccone, MD, Tawia Apenteng, MD
Reviewer Name:
Samir S. Shah, MD, MSCE
Clinical Question:

Are there benefits to starting TPN early in critically ill neonates?

To use or not to use IV magnesium sulfate for severe asthmatics

Posted December 28th, 2007 by standages
in
Author Name(s):
Melissa Lerman MD, Calies Sauk-Schubert MD, Joanne Smith MD, Steve Standage MD
Reviewer Name:
Ronald C. Rubenstein, MD, PhD
Clinical Question:

What is the utility of intravenous magnesium sulfate in improving clinical symptoms or reducing admission in pediatric patients suffering from acute asthma?

DVT Therapy in Children

Posted October 19th, 2007 by goyaln
in
Author Name(s):
Adam Himebauch, MD, Jasmine Karalakulasingam, MD, and Neera Goyal, MD
Reviewer Name:
James Guevara, MD, MPH
Clinical Question:

What is the efficacy of anti-coagulation therapy for acute and recurrent venous thromboembolism (VTE) in children?
What is the evidence that prophylactic anticoagulation in pediatric patients for those at high risk for VTE is safe and effective?

ESBL-Producing Bacteria and Third Generation Cephalosporins: Implications for Empiric Therapy and Formulary Changes

Posted August 29th, 2007 by leegr
in
Author Name(s):
Grace Lee, MD; Allison Wahl, MD, MPH
Reviewer Name:
Ron Keren, MD, MPH
Clinical Question:

1. Does the restricted usage of ceftazidime result in reduced third-generation cephalosporin resistance?
2. Does the replacement of third generation cephalosporins with cefepime for empiric treatment of bacterial infection result in improved clinical outcomes?

Timing of Transition to Oral Antibiotics for Acute Hematogenous Osteomyelitis

Posted August 6th, 2007 by desai
in
Author Name(s):
David Barrett, MD, PhD; Antonella Cianferoni, MD, PhD
Reviewer Name:
David Rubin, MD, MSCE
Clinical Question:

When can a transition from initial IV antibiotic therapy to oral antibiotics be made in the treatment of uncomplicated acute hematogenous osteomyelitis?

Corticosteroids in upper airway obstruction due to non-croup infections

Posted August 6th, 2007 by desai
in
Author Name(s):
Cheryl Clarkin, MD
Reviewer Name:
James Guevara, MD
Clinical Question:

Are corticosteroids useful in preventing upper airway obstruction due to peritonsillar abscess, retropharyngeal abscess or infectious mononucleosis?

Role of H2 antagonists in Treating Patients with Acute Hypersensitivity Reactions

Posted June 9th, 2007 by author
in
Author Name(s):
Lisa Nash, MD; Kavita Parikh, MD; Halden Scott, MD
Reviewer Name:
Joseph Zorc, MD
Clinical Question:

Does the addition of H2 antagonists to standard therapy improve the resolution of acute hypersensitivity symptoms in children who present to the emergency department?

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